You will have to evaluate what suits your needs, and you can access both software stacks. You summarize them in two short sentences - readers cannot give qualified advice based on it.
You can have a look at a sample code written by a R.NET contributor (skyguy94) in the rdotnet-onboarding guide under solutions/WebApp .
Note that, as I understand (I am not doing web dev) IIS interferes with the REngine modifications of the PATH, so see for instance this discussion to make things work. the PATH environment variable must be changed before running.
You can have a look at a sample code written by a R.NET contributor (skyguy94) in the rdotnet-onboarding guide under solutions/WebApp .
Note that, as I understand (I am not doing web dev) IIS interferes with the REngine modifications of the PATH, so see for instance this discussion to make things work. the PATH environment variable must be changed before running.